Phenotypic screening identifies a new oxazolone inhibitor of necroptosis and neuroinflammation

Necroptosis is a regulated form of necrosis, which may be critical in the pathogenesis of neurodegenerative diseases. Neuroinflammation, characterized by the activation of glial cells such as microglia, is closely linked with neurodegenerative pathways and constitutes a major mechanism of neural dam...

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Detalles Bibliográficos
Autores principales: Oliveira, Sara R., Dionísio, Pedro A., Brito, Hugo, Franco, Lídia, Rodrigues, Catarina A. B., Guedes, Rita C., Afonso, Carlos A. M., Amaral, Joana D., Rodrigues, Cecília M. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060125/
https://www.ncbi.nlm.nih.gov/pubmed/30062059
http://dx.doi.org/10.1038/s41420-018-0067-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060125/
https://www.ncbi.nlm.nih.gov/pubmed/30062059
http://dx.doi.org/10.1038/s41420-018-0067-0

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