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Phenotypic screening identifies a new oxazolone inhibitor of necroptosis and neuroinflammation
Necroptosis is a regulated form of necrosis, which may be critical in the pathogenesis of neurodegenerative diseases. Neuroinflammation, characterized by the activation of glial cells such as microglia, is closely linked with neurodegenerative pathways and constitutes a major mechanism of neural dam...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060125/ https://www.ncbi.nlm.nih.gov/pubmed/30062059 http://dx.doi.org/10.1038/s41420-018-0067-0 |