BRD4 inhibitor JQ1 inhibits and reverses mechanical injury-induced corneal scarring

Corneal scarring is characterized by the improper deposition of extracellular matrix components and myofibroblast differentiation from keratocytes. The bromodomain-containing protein 4 (BRD4) inhibitor JQ1 has been shown to attenuate pathological fibrosis. The present study aimed to explore the pote...

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Detalles Bibliográficos
Autores principales: Qu, Mingli, Zhang, Xiaoping, Hu, Xiaoli, Dong, Muchen, Pan, Xiaojing, Bian, Jiang, Zhou, Qingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060126/
https://www.ncbi.nlm.nih.gov/pubmed/30062054
http://dx.doi.org/10.1038/s41420-018-0066-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060126/
https://www.ncbi.nlm.nih.gov/pubmed/30062054
http://dx.doi.org/10.1038/s41420-018-0066-1

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