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Differential regulation of the Wnt/β-catenin pathway by hepatitis C virus recombinants expressing core from various genotypes

Clinical studies have suggested association of some hepatitis C virus (HCV) subtypes or isolates with progression toward hepatocellular carcinoma (HCC). HCV core protein has been reported to interfere with host Wnt/β-catenin pathway, a cell fate-determining pathway, which plays a major role in HCC....

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Detalles Bibliográficos
Autores principales: Aicher, Stephanie, Kakkanas, Athanasios, Cohen, Lisette, Blumen, Brigitte, Oprisan, Gabriela, Njouom, Richard, Meurs, Eliane F., Mavromara, Penelope, Martin, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060129/
https://www.ncbi.nlm.nih.gov/pubmed/30046100
http://dx.doi.org/10.1038/s41598-018-29078-2