The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation

Nucleosome assembly proteins (NAPs) are histone chaperones with an important role in chromatin structure and epigenetic regulation of gene expression. We find that high gene expression levels of mouse Nap1l3 are restricted to haematopoietic stem cells (HSCs) in mice. Importantly, with shRNA or CRISP...

Descripción completa

Detalles Bibliográficos
Autores principales: Heshmati, Yaser, Kharazi, Shabnam, Türköz, Gözde, Chang, David, Kamali Dolatabadi, Esmat, Boström, Johan, Krstic, Aleksandra, Boukoura, Theodora, Wagner, Emma, Kadri, Nadir, Månsson, Robert, Altun, Mikael, Qian, Hong, Walfridsson, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060140/
https://www.ncbi.nlm.nih.gov/pubmed/30046127
http://dx.doi.org/10.1038/s41598-018-29518-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060140/
https://www.ncbi.nlm.nih.gov/pubmed/30046127
http://dx.doi.org/10.1038/s41598-018-29518-z

Ejemplares similares