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Pontin/Tip49 negatively regulates JNK-mediated cell death in Drosophila

Pontin (Pont), also known as Tip49, encodes a member of the AAA+ (ATPases Associated with Diverse Cellular Activities) superfamily and plays pivotal roles in cell proliferation and growth, yet its function in cell death has remained poorly understood. Here we performed a genetic screen for dominant...

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Detalles Bibliográficos
Autores principales: Wang, Xingjun, Huang, Xirui, Wu, Chenxi, Xue, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060144/
https://www.ncbi.nlm.nih.gov/pubmed/30062057
http://dx.doi.org/10.1038/s41420-018-0074-1