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Metabolomic analysis of mouse prefrontal cortex reveals upregulated analytes during wakefulness compared to sleep

By identifying endogenous molecules in brain extracellular fluid metabolomics can provide insight into the regulatory mechanisms and functions of sleep. Here we studied how the cortical metabolome changes during sleep, sleep deprivation and spontaneous wakefulness. Mice were implanted with electrode...

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Detalles Bibliográficos
Autores principales: Bourdon, Allen K., Spano, Giovanna Maria, Marshall, William, Bellesi, Michele, Tononi, Giulio, Serra, Pier Andrea, Baghdoyan, Helen A., Lydic, Ralph, Campagna, Shawn R., Cirelli, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060152/
https://www.ncbi.nlm.nih.gov/pubmed/30046159
http://dx.doi.org/10.1038/s41598-018-29511-6