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Massively parallel sequencing of cell-free DNA in plasma for detecting gynaecological tumour-associated copy number alteration

The discovery of circulating tumour DNA molecules created a paradigm shift in tumour biomarkers as predictors of recurrence. Non-invasive prenatal testing (NIPT) to detect circulating cell-free foetal DNA in maternal plasma is increasingly recognised as a valuable substitute to perceive foetal copy...

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Detalles Bibliográficos
Autores principales: Nakabayashi, Makoto, Kawashima, Akihiro, Yasuhara, Rika, Hayakawa, Yosuke, Miyamoto, Shingo, Iizuka, Chiaki, Sekizawa, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060170/
https://www.ncbi.nlm.nih.gov/pubmed/30046040
http://dx.doi.org/10.1038/s41598-018-29381-y