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Checkpoint Blockade Rescues the Repressive Effect of Histone Deacetylases Inhibitors on γδ T Cell Function

Histone deacetylases (HDAC) are one of the key epigenetic modifiers that control chromatin accessibility and gene expression. Their role in tumorigenesis is well established and HDAC inhibitors have emerged as an effective treatment modality. HDAC inhibitors have been investigated for their specific...

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Detalles Bibliográficos
Autores principales: Bhat, Sajad A., Vedpathak, Disha Mohan, Chiplunkar, Shubhada V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060239/
https://www.ncbi.nlm.nih.gov/pubmed/30072989
http://dx.doi.org/10.3389/fimmu.2018.01615