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Checkpoint Blockade Rescues the Repressive Effect of Histone Deacetylases Inhibitors on γδ T Cell Function
Histone deacetylases (HDAC) are one of the key epigenetic modifiers that control chromatin accessibility and gene expression. Their role in tumorigenesis is well established and HDAC inhibitors have emerged as an effective treatment modality. HDAC inhibitors have been investigated for their specific...
Autores principales: | Bhat, Sajad A., Vedpathak, Disha Mohan, Chiplunkar, Shubhada V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060239/ https://www.ncbi.nlm.nih.gov/pubmed/30072989 http://dx.doi.org/10.3389/fimmu.2018.01615 |
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