Distinct Phenotypes of Shank2 Mouse Models Reflect Neuropsychiatric Spectrum Disorders of Human Patients With SHANK2 Variants

The SHANK scaffolding proteins are important organizers for signaling proteins in the postsynapse of excitatory neurons. The functional significance of SHANK proteins becomes apparent by the wide spectrum of neurodevelopmental and neuropsychiatric disorders associated with SHANK variants in human pa...

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Detalles Bibliográficos
Autores principales: Eltokhi, Ahmed, Rappold, Gudrun, Sprengel, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060255/
https://www.ncbi.nlm.nih.gov/pubmed/30072871
http://dx.doi.org/10.3389/fnmol.2018.00240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060255/
https://www.ncbi.nlm.nih.gov/pubmed/30072871
http://dx.doi.org/10.3389/fnmol.2018.00240

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