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Imaging Calcium in Hippocampal Presynaptic Terminals With a Ratiometric Calcium Sensor in a Novel Transgenic Mouse

Genetically encoded calcium indicators (GECIs) have gained widespread use for measurement of neuronal activity but their low expression levels in transgenic mice tend to limit sensitivity. We have developed a transgenic mouse line (SyG37) that expresses a ratiometric calcium sensor, SyGCaMP2-mCherry...

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Detalles Bibliográficos
Autores principales: Al-Osta, Ibrahim, Mucha, Mariusz, Pereda, Daniel, Piqué-Gili, Marta, Okorocha, Albert E., Thomas, Roisin, Hartell, Nicholas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060260/
https://www.ncbi.nlm.nih.gov/pubmed/30072872
http://dx.doi.org/10.3389/fncel.2018.00209