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Centrally Administered Cortistation-14 Induces Antidepressant-Like Effects in Mice via Mediating Ghrelin and GABA(A) Receptor Signaling Pathway

Cortistatin-14 (CST-14), a recently discovered cyclic neuropeptide, can bind to all five cloned somatostatin receptors (SSTRs) and ghrelin receptor to exert its biological activities and co-exists with GABA within the cortex and hippocampus. However, the role of CST-14 in the control of depression p...

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Detalles Bibliográficos
Autores principales: Jiang, JinHong, Peng, YaLi, Liang, XueYa, Li, Shu, Chang, Xin, Li, LongFei, Chang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060333/
https://www.ncbi.nlm.nih.gov/pubmed/30072893
http://dx.doi.org/10.3389/fphar.2018.00767