N-acetylcysteine suppresses colistimethate sodium-induced nephrotoxicity via activation of SOD2, eNOS, and MMP3 protein expressions

Objective: To investigate the molecular mechanisms of colistimethate sodium-induced nephrotoxicity and the protective effect of N-acetylcysteine (NAC) against nephrotoxicity. Methods: Twenty-eight Wistar rats were divided into four groups comprised of control, colistin, NAC, and colistin–NAC co-trea...

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Detalles Bibliográficos
Autores principales: Ceylan, Bahadir, Ozansoy, Mehmet, Kılıç, Ülkan, Yozgat, Yasemin, Ercan, Çilem, Yıldız, Pelin, Aslan, Turan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Laboratory Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060374/
https://www.ncbi.nlm.nih.gov/pubmed/30035652
http://dx.doi.org/10.1080/0886022X.2018.1489286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060374/
https://www.ncbi.nlm.nih.gov/pubmed/30035652
http://dx.doi.org/10.1080/0886022X.2018.1489286

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