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Intravenous delivery of a liposomal formulation of voriconazole improves drug pharmacokinetics, tissue distribution, and enhances antifungal activity

Voriconazole (VCZ), a triazole with a large spectrum of action is one of the most recommended antifungal agents as the first line therapy against several clinically important systemic fungal infections, including those by Candida albicans. This antifungal has moderate water solubility and exhibits a...

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Detalles Bibliográficos
Autores principales: Veloso, Danillo F. M. C., Benedetti, Naiara I. G. M., Ávila, Renato I., Bastos, Thiago S. A., Silva, Thaísa C., Silva, Maria R. R., Batista, Aline C., Valadares, Marize C., Lima, Eliana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060385/
https://www.ncbi.nlm.nih.gov/pubmed/30044149
http://dx.doi.org/10.1080/10717544.2018.1492046