Overexpression of eukaryotic initiation factor 5A (eIF5A) affects susceptibility to benznidazole in Trypanosoma cruzi populations

Eukaryotic initiation factor 5A (eIF5A) is a conserved protein with an essential role in translation elongation. Using one and two-dimensional western blotting, we showed that the eIF5A protein level was 2-fold lower in benznidazole (BZ)-resistant (BZR and 17LER) Trypanosoma cruzi populations than i...

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Detalles Bibliográficos
Autores principales: Moreira, Douglas de Souza, Duarte, Ana Paula, Pais, Fabiano Sviatopolk Mirsky, da Silva-Pereira, Rosiane Aparecida, Romanha, Alvaro José, Schenkman, Sergio, Murta, Silvane Maria Fonseca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060400/
https://www.ncbi.nlm.nih.gov/pubmed/30066751
http://dx.doi.org/10.1590/0074-02760180162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060400/
https://www.ncbi.nlm.nih.gov/pubmed/30066751
http://dx.doi.org/10.1590/0074-02760180162

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