Neuroprotection Against MPP(+)-Induced Cytotoxicity Through the Activation of PI3-K/Akt/GSK3β/MEF2D Signaling Pathway by Rhynchophylline, the Major Tetracyclic Oxindole Alkaloid Isolated From Uncaria rhynchophylla

Rhynchophylline is a major tetracyclic oxindole alkaloid in Uncaria rhynchophylla, which has been extensively used as traditional herb medicine for the prevention of convulsions and hypertension. However, there is still little evidence about the neuroprotective effects of rhynchophylline for Parkins...

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Detalles Bibliográficos
Autores principales: Hu, Shengquan, Mak, Shinghung, Zuo, Xialin, Li, Haitao, Wang, Yuqiang, Han, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060423/
https://www.ncbi.nlm.nih.gov/pubmed/30072894
http://dx.doi.org/10.3389/fphar.2018.00768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060423/
https://www.ncbi.nlm.nih.gov/pubmed/30072894
http://dx.doi.org/10.3389/fphar.2018.00768

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