Levels of ADAM10 are reduced in Alzheimer’s disease CSF

BACKGROUND: The disintegrin metalloproteinase 10 (ADAM10) is the main α-secretase acting in the non-amyloidogenic processing of the amyloid precursor protein. This study assesses whether ADAM10 is present in cerebrospinal fluid (CSF), and whether it has potential as a biomarker for Alzheimer’s disea...

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Detalles Bibliográficos
Autores principales: Sogorb-Esteve, Aitana, García-Ayllón, María-Salud, Gobom, Johan, Alom, Jordi, Zetterberg, Henrik, Blennow, Kaj, Sáez-Valero, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060469/
https://www.ncbi.nlm.nih.gov/pubmed/30045733
http://dx.doi.org/10.1186/s12974-018-1255-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060469/
https://www.ncbi.nlm.nih.gov/pubmed/30045733
http://dx.doi.org/10.1186/s12974-018-1255-9

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