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Levels of ADAM10 are reduced in Alzheimer’s disease CSF

BACKGROUND: The disintegrin metalloproteinase 10 (ADAM10) is the main α-secretase acting in the non-amyloidogenic processing of the amyloid precursor protein. This study assesses whether ADAM10 is present in cerebrospinal fluid (CSF), and whether it has potential as a biomarker for Alzheimer’s disea...

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Detalles Bibliográficos
Autores principales:	Sogorb-Esteve, Aitana, García-Ayllón, María-Salud, Gobom, Johan, Alom, Jordi, Zetterberg, Henrik, Blennow, Kaj, Sáez-Valero, Javier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060469/ https://www.ncbi.nlm.nih.gov/pubmed/30045733 http://dx.doi.org/10.1186/s12974-018-1255-9

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