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A two-stage microbial association mapping framework with advanced FDR control

BACKGROUND: In microbiome studies, it is important to detect taxa which are associated with pathological outcomes at the lowest definable taxonomic rank, such as genus or species. Traditionally, taxa at the target rank are tested for individual association, followed by the Benjamini-Hochberg (BH) pr...

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Detalles Bibliográficos
Autores principales: Hu, Jiyuan, Koh, Hyunwook, He, Linchen, Liu, Menghan, Blaser, Martin J., Li, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060480/
https://www.ncbi.nlm.nih.gov/pubmed/30045760
http://dx.doi.org/10.1186/s40168-018-0517-1