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A two-stage microbial association mapping framework with advanced FDR control
BACKGROUND: In microbiome studies, it is important to detect taxa which are associated with pathological outcomes at the lowest definable taxonomic rank, such as genus or species. Traditionally, taxa at the target rank are tested for individual association, followed by the Benjamini-Hochberg (BH) pr...
Autores principales: | Hu, Jiyuan, Koh, Hyunwook, He, Linchen, Liu, Menghan, Blaser, Martin J., Li, Huilin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060480/ https://www.ncbi.nlm.nih.gov/pubmed/30045760 http://dx.doi.org/10.1186/s40168-018-0517-1 |
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