Cargando…

Activation of the reninangiotensin system in mice aggravates mechanical loadinginduced knee osteoarthritis

Epidemiological studies have shown an association between hypertension and knee osteoarthritis (OA). The purpose of this study was to investigate whether activation of the renin–angiotensin system (RAS) can aggravate mechanical loading-induced knee OA in mice. Eight-week-old male Tsukuba hypertensiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamagishi, Kotaro, Tsukamoto, Ichiro, Nakamura, Fumihisa, Hashimoto, Kazuhiko, Ohtani, Kazuhiro, Akagi, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060485/
https://www.ncbi.nlm.nih.gov/pubmed/30043596
http://dx.doi.org/10.4081/ejh.2018.2930