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Activation of the reninangiotensin system in mice aggravates mechanical loadinginduced knee osteoarthritis
Epidemiological studies have shown an association between hypertension and knee osteoarthritis (OA). The purpose of this study was to investigate whether activation of the renin–angiotensin system (RAS) can aggravate mechanical loading-induced knee OA in mice. Eight-week-old male Tsukuba hypertensiv...
Autores principales: | Yamagishi, Kotaro, Tsukamoto, Ichiro, Nakamura, Fumihisa, Hashimoto, Kazuhiko, Ohtani, Kazuhiro, Akagi, Masao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060485/ https://www.ncbi.nlm.nih.gov/pubmed/30043596 http://dx.doi.org/10.4081/ejh.2018.2930 |
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