Cargando…

Activation of the reninangiotensin system in mice aggravates mechanical loadinginduced knee osteoarthritis

Epidemiological studies have shown an association between hypertension and knee osteoarthritis (OA). The purpose of this study was to investigate whether activation of the renin–angiotensin system (RAS) can aggravate mechanical loading-induced knee OA in mice. Eight-week-old male Tsukuba hypertensiv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yamagishi, Kotaro, Tsukamoto, Ichiro, Nakamura, Fumihisa, Hashimoto, Kazuhiko, Ohtani, Kazuhiro, Akagi, Masao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PAGEPress Publications, Pavia, Italy 2018
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060485/ https://www.ncbi.nlm.nih.gov/pubmed/30043596 http://dx.doi.org/10.4081/ejh.2018.2930

Ejemplares similares

Lectin-like, oxidized low-density lipoprotein receptor-1-deficient mice show resistance to age-related knee osteoarthritis
por: Hashimoto, Kazuhiko, et al.
Publicado: (2017)

Cyclic compressive loading activates angiotensin II type 1 receptor in articular chondrocytes and stimulates hypertrophic differentiation through a G‐protein‐dependent pathway
por: Nakamura, Fumihisa, et al.
Publicado: (2018)

Treatment of a patient suffering from posttraumatic painful neuromas formed at the bilateral digital nerves of the left middle finger using two neurovascular island flaps
por: Iemura, Shunki, et al.
Publicado: (2018)

Rapidly progressive osteoarthritis in the medial patellar facet due to lateral femoral placement after medial unicompartmental knee arthroplasty. A case report
por: Inoue, Shinji, et al.
Publicado: (2021)

LOX-1 deficient mice show resistance to zymosan-induced arthritis
por: Hashimoto, Kazuhiko, et al.
Publicado: (2018)

How proximal femur fracture patients aged 65 and older fare in survival and cause of death 5+ years after surgery: A long-term follow-up
por: Hashimoto, Kazuhiko, et al.
Publicado: (2023)

The role of oxidation of low-density lipids in pathogenesis of osteoarthritis: A narrative review
por: Hashimoto, Kazuhiko, et al.
Publicado: (2020)

Study of serum and urinary markers of the reninangiotensin-aldosterone system in myelomeningocele patients with renal injury detected by DMSA
por: do Amaral, Cássia Maria Carvalho Abrantes, et al.
Publicado: (2020)

Activating types 1 and 2 angiotensin II receptors modulate the hypertrophic differentiation of chondrocytes()
por: Tsukamoto, Ichiro, et al.
Publicado: (2013)

Extra-articular synovial osteochondroma of the Hoffa's fat pad involving the patellar tendon: A case report and literature review
por: Hashimoto, Kazuhiko, et al.
Publicado: (2020)

Referencing the Tibial Plateau With a Probe Improves the Accuracy of the Posterior Slope in Medial Unicompartmental Knee Arthroplasty
por: Akagi, Masao, et al.
Publicado: (2022)

A direct referencing method of the tibial plateau for the posterior tibial slope in medial unicompartmental knee arthroplasty
por: Akagi, Masao, et al.
Publicado: (2022)

Three-dimensional finite-element analysis of aggravating medial meniscus tears on knee osteoarthritis
por: Li, Lan, et al.
Publicado: (2019)

SOST Deficiency Aggravates Osteoarthritis in Mice by Promoting Sclerosis of Subchondral Bone
por: Li, Jingyu, et al.
Publicado: (2019)

A Case of Atypical Lipomatous Tumor that Dedifferentiated with Second Recurrence after Additional Resection
por: Hashimoto, Kazuhiko, et al.
Publicado: (2018)

Characterization of PD-1/PD-L1 Immune Checkpoint Expression in Osteosarcoma
por: Hashimoto, Kazuhiko, et al.
Publicado: (2020)

Lung Adenocarcinoma Presenting as a Soft Tissue Metastasis to the Shoulder: A Case Report
por: Hashimoto, Kazuhiko, et al.
Publicado: (2021)

Disorganization of chondrocyte columns in the growth plate does not aggravate experimental osteoarthritis in mice
por: Lamuedra, Ana, et al.
Publicado: (2020)

Osteoarthritis Pain in Old Mice Aggravates Neuroinflammation and Frailty: The Positive Effect of Morphine Treatment
por: Amodeo, Giada, et al.
Publicado: (2022)

Treatment of angiomatoid fibrous histiocytoma after unplanned excision: a case report
por: Hashimoto, Kazuhiko, et al.
Publicado: (2018)

Suspension Arthroplasty Combined with Ligament Reconstruction of the Thumb Carpometacarpal Joint to Salvage Two Failed Arthroplasties: A Case Report
por: Kakinoki, Ryosuke, et al.
Publicado: (2017)

Clinical features and outcomes of primary bone and soft tissue sarcomas in adolescents and young adults
por: Hashimoto, Kazuhiko, et al.
Publicado: (2020)

Surgical management of sarcoma in adolescent and young adult patients
por: Hashimoto, Kazuhiko, et al.
Publicado: (2020)

Outcomes of comprehensive treatment for primary osteosarcoma
por: Hashimoto, Kazuhiko, et al.
Publicado: (2020)

Characterization of PD-1/PD-L1 immune checkpoint expression in soft tissue sarcomas
por: Hashimoto, Kazuhiko, et al.
Publicado: (2021)

Clinicopathological Assessment of Cancer/Testis Antigens NY-ESO-1 and MAGE-A4 in Highly Aggressive Soft Tissue Sarcomas
por: Hashimoto, Kazuhiko, et al.
Publicado: (2022)

Malignant giant cell tumor of toe: A case report and review of literature
por: Hashimoto, Kazuhiko, et al.
Publicado: (2022)

Increased HIF-1α in Knee Osteoarthritis Aggravate Synovial Fibrosis via Fibroblast-Like Synoviocyte Pyroptosis
por: Zhang, Li, et al.
Publicado: (2019)

Intraneural synovial sarcoma of the tibial nerve
por: Hashimoto, Kazuhiko, et al.
Publicado: (2018)

Successful treatment with denosumab in a patient with sacral giant cell tumor of bone refractory to combination therapy with arterial embolization and zoledronic acid: A case report
por: Nishimura, Shunji, et al.
Publicado: (2017)

Inflammatory Undifferentiated Pleomorphic Sarcoma Mimicking Bacteremia in an Elderly Patient: A Case Report
por: Hashimoto, Kazuhiko, et al.
Publicado: (2021)

Immunohistochemical expression and clinicopathological assessment of PD-1, PD-L1, NY-ESO-1, and MAGE-A4 expression in highly aggressive soft tissue sarcomas
por: Hashimoto, Kazuhiko, et al.
Publicado: (2022)

Limitations and usefulness of biopsy techniques for the diagnosis of metastatic bone and soft tissue tumors
por: Hashimoto, Kazuhiko, et al.
Publicado: (2021)

Characterizing inflammatory markers in highly aggressive soft tissue sarcomas
por: Hashimoto, Kazuhiko, et al.
Publicado: (2022)

Aggressive intraosseous lipoma of the scapula: A case report
por: Oka, Naohiro, et al.
Publicado: (2023)

Plasminogen activator inhibitor-1 deficiency enhances subchondral osteopenia after induction of osteoarthritis in mice
por: Moritake, Akihiro, et al.
Publicado: (2017)

Blocking of checkpoint receptor PD-L1 aggravates osteoarthritis in macrophage-dependent manner in the mice model
por: Liu, Shenghou, et al.
Publicado: (2019)

Expressions of Local Renin-Angiotensin System Components in Chondrocytes
por: Tsukamoto, I., et al.
Publicado: (2014)

Degenerative Meniscus in Knee Osteoarthritis: From Pathology to Treatment
por: Ozeki, Nobutake, et al.
Publicado: (2022)

Role of autophagy in the progression of osteoarthritis: The autophagy inhibitor, 3-methyladenine, aggravates the severity of experimental osteoarthritis
por: Cheng, Ni-Tao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_o7f0vngst9qffpnhhuoedamlbl