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Elevated levels of matrix metalloproteinases reflect severity and extent of disease in tuberculosis-diabetes co-morbidity and are predominantly reversed following standard anti-tuberculosis or metformin treatment

BACKGROUND: Matrix metalloproteinases (MMPs) are considered to be key mediators of tuberculosis (TB) pathology but their role in tuberculosis – diabetes comorbidity (TB-DM) is not well understood. METHODS: To study the association of MMP levels with severity and extent of disease as well as bacteria...

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Detalles Bibliográficos
Autores principales: Kumar, Nathella P., Moideen, Kadar, Viswanathan, Vijay, Shruthi, Basavaradhya S., Sivakumar, Shanmugam, Menon, Pradeep A., Kornfeld, Hardy, Babu, Subash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060542/
https://www.ncbi.nlm.nih.gov/pubmed/30045688
http://dx.doi.org/10.1186/s12879-018-3246-y