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HuD Is a Neural Translation Enhancer Acting on mTORC1-Responsive Genes and Counteracted by the Y3 Small Non-coding RNA

The RNA-binding protein HuD promotes neurogenesis and favors recovery from peripheral axon injury. HuD interacts with many mRNAs, altering both stability and translation efficiency. We generated a nucleotide resolution map of the HuD RNA interactome in motor neuron-like cells, identifying HuD target...

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Detalles Bibliográficos
Autores principales: Tebaldi, Toma, Zuccotti, Paola, Peroni, Daniele, Köhn, Marcel, Gasperini, Lisa, Potrich, Valentina, Bonazza, Veronica, Dudnakova, Tatiana, Rossi, Annalisa, Sanguinetti, Guido, Conti, Luciano, Macchi, Paolo, D’Agostino, Vito, Viero, Gabriella, Tollervey, David, Hüttelmaier, Stefan, Quattrone, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060611/
https://www.ncbi.nlm.nih.gov/pubmed/30029004
http://dx.doi.org/10.1016/j.molcel.2018.06.032