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HuD Is a Neural Translation Enhancer Acting on mTORC1-Responsive Genes and Counteracted by the Y3 Small Non-coding RNA
The RNA-binding protein HuD promotes neurogenesis and favors recovery from peripheral axon injury. HuD interacts with many mRNAs, altering both stability and translation efficiency. We generated a nucleotide resolution map of the HuD RNA interactome in motor neuron-like cells, identifying HuD target...
Autores principales: | Tebaldi, Toma, Zuccotti, Paola, Peroni, Daniele, Köhn, Marcel, Gasperini, Lisa, Potrich, Valentina, Bonazza, Veronica, Dudnakova, Tatiana, Rossi, Annalisa, Sanguinetti, Guido, Conti, Luciano, Macchi, Paolo, D’Agostino, Vito, Viero, Gabriella, Tollervey, David, Hüttelmaier, Stefan, Quattrone, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060611/ https://www.ncbi.nlm.nih.gov/pubmed/30029004 http://dx.doi.org/10.1016/j.molcel.2018.06.032 |
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