Global metabolic changes induced by plant-derived pyrrolizidine alkaloids following a human poisoning outbreak and in a mouse model

Several hundred cases of Hirmi Valley Liver Disease (HVLD), an often fatal liver injury, occurred from 2001 to 2011 in a cluster of rural villages in Tigray, Ethiopia. HVLD is principally caused by contamination of the food supply with plant derived pyrrolizidine alkaloids (PAs), with high exposure...

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Detalles Bibliográficos
Autores principales: Robinson, Oliver, Toledano, Mireille B., Sands, Caroline, Beckonert, Olaf, J. Want, Elizabeth, Goldin, Rob, Hauser, Michael L., Fenwick, Alan, Thursz, Mark R., Coen, Muireann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060677/
https://www.ncbi.nlm.nih.gov/pubmed/30090460
http://dx.doi.org/10.1039/c6tx00221h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060677/
https://www.ncbi.nlm.nih.gov/pubmed/30090460
http://dx.doi.org/10.1039/c6tx00221h

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