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Ratiometric delivery of two therapeutic candidates with inherently dissimilar physicochemical property through pH-sensitive core–shell nanoparticles targeting the heterogeneous tumor cells of glioma

Currently, combination drug therapy is one of the most effective approaches to glioma treatment. However, due to the inherent dissimilar pharmacokinetics of individual drugs and blood brain barriers, it was difficult for the concomitant drugs to simultaneously be delivered to glioma in an optimal do...

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Detalles Bibliográficos
Autores principales: Xu, He-Lin, Fan, Zi-Liang, ZhuGe, De-Li, Tong, Meng-Qi, Shen, Bi-Xin, Lin, Meng-Ting, Zhu, Qun-Yan, Jin, Bing-Hui, Sohawon, Yasin, Yao, Qing, Zhao, Ying-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060705/
https://www.ncbi.nlm.nih.gov/pubmed/29869524
http://dx.doi.org/10.1080/10717544.2018.1474974