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Expansion of gene clusters, circular orders, and the shortest Hamiltonian path problem
Clusters of paralogous genes such as the famous HOX cluster of developmental transcription factors tend to evolve by stepwise duplication of its members, often involving unequal crossing over. Gene conversion and possibly other mechanisms of concerted evolution further obfuscate the phylogenetic rel...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060901/ https://www.ncbi.nlm.nih.gov/pubmed/29260295 http://dx.doi.org/10.1007/s00285-017-1197-3 |