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Expansion of gene clusters, circular orders, and the shortest Hamiltonian path problem

Clusters of paralogous genes such as the famous HOX cluster of developmental transcription factors tend to evolve by stepwise duplication of its members, often involving unequal crossing over. Gene conversion and possibly other mechanisms of concerted evolution further obfuscate the phylogenetic rel...

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Detalles Bibliográficos
Autores principales: Prohaska, Sonja J., Berkemer, Sarah J., Gärtner, Fabian, Gatter, Thomas, Retzlaff, Nancy, Höner zu Siederdissen, Christian, Stadler, Peter F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060901/
https://www.ncbi.nlm.nih.gov/pubmed/29260295
http://dx.doi.org/10.1007/s00285-017-1197-3