Population Pharmacokinetic Analysis and Model-Based Simulations of Aripiprazole for a 1-Day Initiation Regimen for the Long-Acting Antipsychotic Aripiprazole Lauroxil

BACKGROUND AND OBJECTIVES: Aripiprazole lauroxil (AL), a long-acting injectable antipsychotic for the treatment of schizophrenia, requires 21 days of oral aripiprazole supplementation upon initiation (21-day initiation regimen). An alternative 1-day initiation regimen utilizing a nano-crystalline mi...

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Detalles Bibliográficos
Autores principales: Hard, Marjie L., Wehr, Angela Y., Sadler, Brian M., Mills, Richard J., von Moltke, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060990/
https://www.ncbi.nlm.nih.gov/pubmed/29943125
http://dx.doi.org/10.1007/s13318-018-0488-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060990/
https://www.ncbi.nlm.nih.gov/pubmed/29943125
http://dx.doi.org/10.1007/s13318-018-0488-4

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