Modeling and simulations to support dose selection for eslicarbazepine acetate therapy in pediatric patients with partial-onset seizures

Modeling and simulations were used to support body weight-based dose selection for eslicarbazepine acetate (ESL) in pediatric subjects aged 4–17 years with partial-onset seizures. A one-compartment pediatric population pharmacokinetic model with formulation-specific first-order absorption, first-ord...

Descripción completa

Detalles Bibliográficos
Autores principales: Sunkaraneni, Soujanya, Ludwig, Elizabeth, Fiedler-Kelly, Jill, Hopkins, Seth, Galluppi, Gerald, Blum, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061080/
https://www.ncbi.nlm.nih.gov/pubmed/29948795
http://dx.doi.org/10.1007/s10928-018-9596-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061080/
https://www.ncbi.nlm.nih.gov/pubmed/29948795
http://dx.doi.org/10.1007/s10928-018-9596-7

Ejemplares similares