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Defining G protein-coupled receptor peptide ligand expressomes and signalomes in human and mouse islets
INTRODUCTION: Islets synthesise and secrete numerous peptides, some of which are known to be important regulators of islet function and glucose homeostasis. In this study, we quantified mRNAs encoding all peptide ligands of islet G protein-coupled receptors (GPCRs) in isolated human and mouse islets...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061145/ https://www.ncbi.nlm.nih.gov/pubmed/29455414 http://dx.doi.org/10.1007/s00018-018-2778-z |