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Synthesis and biological investigations of 3β-aminotropane arylamide derivatives with atypical antipsychotic profile

This work is a continuation of our previous research, concentrating this time on lead structure modification to increase the 5-HT(1A) receptor affinity and water solubility of designed compounds. Therefore, the compounds synthesised within the present project included structural analogues of 3β-acyl...

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Detalles Bibliográficos
Autores principales: Stefanowicz, Jacek, Słowiński, Tomasz, Wróbel, Martyna Z., Ślifirski, Grzegorz, Dawidowski, Maciej, Stefanowicz, Zdzisława, Jastrzębska-Więsek, Magdalena, Partyka, Anna, Wesołowska, Anna, Turło, Jadwiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061170/
https://www.ncbi.nlm.nih.gov/pubmed/30100693
http://dx.doi.org/10.1007/s00044-018-2203-z