Enhanced endosomal escape by photothermal activation for improved small interfering RNA delivery and antitumor effect

BACKGROUND: Effective endosomal escape is still a critical bottleneck for intracellular delivery of small interfering RNAs (siRNAs) to maximize their therapeutic efficacy. To overcome this obstacle, we have developed a photothermally triggered system by using the near-infrared (NIR) irradiation to a...

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Detalles Bibliográficos
Autores principales: Yang, Xi, Fan, Bo, Gao, Wei, Li, Liping, Li, Tingting, Sun, Jinghua, Peng, Xiaoyang, Li, Xiaoyan, Wang, Zhenjun, Wang, Binquan, Zhang, Ruiping, Xie, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061202/
https://www.ncbi.nlm.nih.gov/pubmed/30087564
http://dx.doi.org/10.2147/IJN.S161908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061202/
https://www.ncbi.nlm.nih.gov/pubmed/30087564
http://dx.doi.org/10.2147/IJN.S161908

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