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Pharmacokinetics of Fentanyl Sublingual Spray in Opioid-Naïve Participants: Results of a Phase 1, Multiple Ascending Dose Study

BACKGROUND AND OBJECTIVES: Fentanyl sublingual spray may be a viable alternative to intravenous (IV) opioids for the treatment of acute pain. As patients with acute pain may include those who have limited prior exposure to opioids, this phase 1, open-label, randomized, multiple ascending-dose study...

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Detalles Bibliográficos
Autores principales: Rauck, Richard L., Oh, D. Alexander, Singla, Neil, Koch, Christian, Parikh, Neha, Nalamachu, Srinivas, Yu, Jin, James, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061414/
https://www.ncbi.nlm.nih.gov/pubmed/29909433
http://dx.doi.org/10.1007/s40261-018-0658-9