Clustering of ABCB1 and CYP2C19 Genetic Variants Predicts Risk of Major Bleeding and Thrombotic Events in Elderly Patients with Acute Coronary Syndrome Receiving Dual Antiplatelet Therapy with Aspirin and Clopidogrel

OBJECTIVE: The clinical efficacy of clopidogrel in secondary prevention of vascular events is hampered by marked inter-patient variability in drug response, which partially depends on genetic make-up. The aim of this pilot prospective study was to evaluate 12-month cardiovascular outcomes in elderly...

Descripción completa

Detalles Bibliográficos
Autores principales: Galeazzi, Roberta, Olivieri, Fabiola, Spazzafumo, Liana, Rose, Giuseppina, Montesanto, Alberto, Giovagnetti, Simona, Cecchini, Sara, Malatesta, Gelsomina, Di Pillo, Raffaele, Antonicelli, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061429/
https://www.ncbi.nlm.nih.gov/pubmed/29936693
http://dx.doi.org/10.1007/s40266-018-0555-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061429/
https://www.ncbi.nlm.nih.gov/pubmed/29936693
http://dx.doi.org/10.1007/s40266-018-0555-1

Ejemplares similares