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Clustering of ABCB1 and CYP2C19 Genetic Variants Predicts Risk of Major Bleeding and Thrombotic Events in Elderly Patients with Acute Coronary Syndrome Receiving Dual Antiplatelet Therapy with Aspirin and Clopidogrel
OBJECTIVE: The clinical efficacy of clopidogrel in secondary prevention of vascular events is hampered by marked inter-patient variability in drug response, which partially depends on genetic make-up. The aim of this pilot prospective study was to evaluate 12-month cardiovascular outcomes in elderly...
Autores principales: | Galeazzi, Roberta, Olivieri, Fabiola, Spazzafumo, Liana, Rose, Giuseppina, Montesanto, Alberto, Giovagnetti, Simona, Cecchini, Sara, Malatesta, Gelsomina, Di Pillo, Raffaele, Antonicelli, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061429/ https://www.ncbi.nlm.nih.gov/pubmed/29936693 http://dx.doi.org/10.1007/s40266-018-0555-1 |
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