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Pharmacological Inhibition of the Skeletal IKKβ Reduces Breast Cancer-Induced Osteolysis

IKKβ has previously been implicated in breast cancer bone metastasis and bone remodelling. However, the contribution of IKKβ expressed by bone cells of the tumour microenvironment to breast cancer-induced osteolysis has yet to be investigated. Here, we studied the effects of the verified selective I...

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Detalles Bibliográficos
Autores principales: Marino, Silvia, Bishop, Ryan T., Mollat, Patrick, Idris, Aymen I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061461/
https://www.ncbi.nlm.nih.gov/pubmed/29455416
http://dx.doi.org/10.1007/s00223-018-0406-4