A randomised Phase II/III study to evaluate the efficacy and safety of orally administered Oxalobacter formigenes to treat primary hyperoxaluria

Primary hyperoxaluria (PH) patients overproduce oxalate because of rare genetic errors in glyoxylate metabolism. Recurrent urolithiasis and/or progressive nephrocalcinosis are PH hallmarks and can lead to kidney damage, systemic oxalosis and death. Based on previous studies, we hypothesised that tre...

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Detalles Bibliográficos
Autores principales: Milliner, Dawn, Hoppe, Bernd, Groothoff, Jaap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061479/
https://www.ncbi.nlm.nih.gov/pubmed/28718073
http://dx.doi.org/10.1007/s00240-017-0998-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061479/
https://www.ncbi.nlm.nih.gov/pubmed/28718073
http://dx.doi.org/10.1007/s00240-017-0998-6

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