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Multifactorial control of the expression of a CRISPR-Cas system by an extracytoplasmic function σ/anti-σ pair and a global regulatory complex

Expression of CRISPR-Cas systems is a prerequisite for their defensive role against invading genetic elements. Yet, much remains unknown about how this crucial step is regulated. We describe a new mechanism controlling CRISPR-cas expression, which requires an extracytoplasmic function (ECF) σ factor...

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Detalles Bibliográficos
Autores principales: Bernal-Bernal, Diego, Abellón-Ruiz, Javier, Iniesta, Antonio A, Pajares-Martínez, Elena, Bastida-Martínez, Eva, Fontes, Marta, Padmanabhan, S, Elías-Arnanz, Montserrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061681/
https://www.ncbi.nlm.nih.gov/pubmed/29893914
http://dx.doi.org/10.1093/nar/gky475