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Multifactorial control of the expression of a CRISPR-Cas system by an extracytoplasmic function σ/anti-σ pair and a global regulatory complex

Expression of CRISPR-Cas systems is a prerequisite for their defensive role against invading genetic elements. Yet, much remains unknown about how this crucial step is regulated. We describe a new mechanism controlling CRISPR-cas expression, which requires an extracytoplasmic function (ECF) σ factor...

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Detalles Bibliográficos
Autores principales:	Bernal-Bernal, Diego, Abellón-Ruiz, Javier, Iniesta, Antonio A, Pajares-Martínez, Elena, Bastida-Martínez, Eva, Fontes, Marta, Padmanabhan, S, Elías-Arnanz, Montserrat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061681/ https://www.ncbi.nlm.nih.gov/pubmed/29893914 http://dx.doi.org/10.1093/nar/gky475

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