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Acute ketamine dysregulates task-related gamma-band oscillations in thalamo-cortical circuits in schizophrenia

Hypofunction of the N-methyl-d-aspartate receptor (NMDAR) has been implicated as a possible mechanism underlying cognitive deficits and aberrant neuronal dynamics in schizophrenia. To test this hypothesis, we first administered a sub-anaesthetic dose of S-ketamine (0.006 mg/kg/min) or saline in a si...

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Detalles Bibliográficos
Autores principales: Grent-‘t-Jong, Tineke, Rivolta, Davide, Gross, Joachim, Gajwani, Ruchika, Lawrie, Stephen M, Schwannauer, Matthias, Heidegger, Tonio, Wibral, Michael, Singer, Wolf, Sauer, Andreas, Scheller, Bertram, Uhlhaas, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061682/
https://www.ncbi.nlm.nih.gov/pubmed/30020423
http://dx.doi.org/10.1093/brain/awy175