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The Role of Endocrine and Dioxin-Like Activity of Extracts of Petroleum Substances in Developmental Toxicity as Detected in a Panel of CALUX Reporter Gene Assays

Recent evidence suggests that the interaction of polycyclic aromatic hydrocarbons (PAHs), present in some petroleum substances (PS), with particular nuclear-hormone-receptors and/or the dioxin (aryl hydrocarbon receptor [AhR]) receptor, may play a role in the prenatal developmental toxicity (PDT) in...

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Detalles Bibliográficos
Autores principales: Kamelia, Lenny, Louisse, Jochem, de Haan, Laura, Maslowska-Gornicz, Anna, Ketelslegers, Hans B, Brouwer, Abraham, Rietjens, Ivonne M C M, Boogaard, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061685/
https://www.ncbi.nlm.nih.gov/pubmed/29726971
http://dx.doi.org/10.1093/toxsci/kfy114