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The histamine H(3) receptor inverse agonist pitolisant reduces body weight in obese mice

The pharmacological profile of pitolisant, a histamine H(3) receptor antagonist/inverse agonist, indicates that this compound might reduce body weight and metabolic disturbances. Therefore, we studied the influence of pitolisant on body weight, water and sucrose intake as well as metabolic disturban...

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Detalles Bibliográficos
Autores principales: Kotańska, Magdalena, Kuder, Kamil J., Szczepańska, Katarzyna, Sapa, Jacek, Kieć-Kononowicz, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061715/
https://www.ncbi.nlm.nih.gov/pubmed/29802412
http://dx.doi.org/10.1007/s00210-018-1516-2