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RecBCD coordinates repair of two ends at a DNA double-strand break, preventing aberrant chromosome amplification

DNA double-strand break (DSB) repair is critical for cell survival. A diverse range of organisms from bacteria to humans rely on homologous recombination for accurate DSB repair. This requires both coordinate action of the two ends of a DSB and stringent control of the resultant DNA replication to p...

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Detalles Bibliográficos
Autores principales: White, Martin A, Azeroglu, Benura, Lopez-Vernaza, Manuel A, Hasan, A M Mahedi, Leach, David R F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061781/
https://www.ncbi.nlm.nih.gov/pubmed/29901759
http://dx.doi.org/10.1093/nar/gky463