Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

In metazoan cells, only a limited number of mini chromosome maintenance (MCM) complexes are fired during S phase, while the majority remain dormant. Several methods have been used to map replication origins, but such methods cannot identify dormant origins. Herein, we determined MCM7-binding sites i...

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Detalles Bibliográficos
Autores principales: Sugimoto, Nozomi, Maehara, Kazumitsu, Yoshida, Kazumasa, Ohkawa, Yasuyuki, Fujita, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061783/
https://www.ncbi.nlm.nih.gov/pubmed/29893900
http://dx.doi.org/10.1093/nar/gky476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061783/
https://www.ncbi.nlm.nih.gov/pubmed/29893900
http://dx.doi.org/10.1093/nar/gky476

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