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The impact of within-host ecology on the fitness of a drug-resistant parasite

BACKGROUND AND OBJECTIVES: The rate of evolution of drug resistance depends on the fitness of resistant pathogens. The fitness of resistant pathogens is reduced by competition with sensitive pathogens in untreated hosts and so enhanced by competitive release in drug-treated hosts. We set out to esti...

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Detalles Bibliográficos
Autores principales: Huijben, Silvie, Chan, Brian H K, Nelson, William A, Read, Andrew F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061792/
https://www.ncbi.nlm.nih.gov/pubmed/30087774
http://dx.doi.org/10.1093/emph/eoy016