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The impact of within-host ecology on the fitness of a drug-resistant parasite
BACKGROUND AND OBJECTIVES: The rate of evolution of drug resistance depends on the fitness of resistant pathogens. The fitness of resistant pathogens is reduced by competition with sensitive pathogens in untreated hosts and so enhanced by competitive release in drug-treated hosts. We set out to esti...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061792/ https://www.ncbi.nlm.nih.gov/pubmed/30087774 http://dx.doi.org/10.1093/emph/eoy016 |