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A CRISPR/molecular beacon hybrid system for live-cell genomic imaging

The clustered regularly interspersed short palindromic repeat (CRISPR) gene-editing system has been repurposed for live-cell genomic imaging, but existing approaches rely on fluorescent protein reporters, making sensitive and continuous imaging difficult. Here, we present a fluorophore-based live-ce...

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Detalles Bibliográficos
Autores principales: Wu, Xiaotian, Mao, Shiqi, Yang, Yantao, Rushdi, Muaz N, Krueger, Christopher J, Chen, Antony K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061827/
https://www.ncbi.nlm.nih.gov/pubmed/29718399
http://dx.doi.org/10.1093/nar/gky304