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Structure and ligand binding of the SAM-V riboswitch

SAM-V is one of the class of riboswitches that bind S-adenosylmethione, regulating gene expression by controlling translation. We have solved the crystal structure of the metY SAM-V riboswitch bound to its SAM ligand at 2.5 Å resolution. The RNA folds as an H-type pseudoknot, with a major-groove tri...

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Detalles Bibliográficos
Autores principales: Huang, Lin, Lilley, David M J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061858/
https://www.ncbi.nlm.nih.gov/pubmed/29931337
http://dx.doi.org/10.1093/nar/gky520